Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Escherichia coli leucine-responsive regulatory protein (Lrp) controls lysyl-tRNA synthetase expression.

FEBS letters - 6 Apr 1992

Gazeau M, Delort F, Dessen P, Blanquet S, Plateau P

Abstract excerpt

Using random Tn10 insertion mutagenesis, we isolated an Escherichia coli mutant strain affected in the regulation of lysU, the gene encoding the inducible form of lysyl-tRNA synthetase. The transposon giving rise to the altered expression of lysU was found inserted within lrp. The latter gene codes for the leucine-responsive regulatory protein (Lrp) which mediates a global response of the bacterium to leucine. An...

Topics

Bacterial Proteins
Base Sequence
Chromosome Mapping
Chromosomes, Bacterial
DNA-Binding Proteins
Escherichia coli
Escherichia coli Proteins
Gene Expression Regulation, Enzymologic
Leucine
Leucine-Responsive Regulatory Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lysine-tRNA Ligase

Molecular Sequence Data

Mutation

Plasmids

Transcription Factors

Source

Identifiers

PMID: 1555652
DOI: 10.1016/0014-5793(92)80857-d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1555652-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Escherichia coli leucine-responsive regulatory protein (Lrp) controls lysyl-tRNA synthetase expression.PMID 1555652Read ↗

Leucine-responsive regulatory protein: a global regulator of gene expression in E. coli.Semantic proximity Read ↗

Regulation of the Escherichia coli lrp gene.Semantic proximity Read ↗

Escherichia coli Lrp (leucine-responsive regulatory protein) does not directly regulate expression of the leu operon promoter.Semantic proximity Read ↗

Differential regulation of two genes encoding lysyl-tRNA synthetases in Escherichia coli: lysU-constitutive mutations compensate for a lysS null mutation.Semantic proximity Read ↗

Roles of the two lysyl-tRNA synthetases of Escherichia coli: analysis of nucleotide sequences and mutant behavior.Semantic proximity Read ↗

The leucine regulon of Escherichia coli K-12: a mutation in rblA alters expression of L-leucine-dependent metabolic operons.Semantic proximity Read ↗

Regulation of lysyl-tRNA synthetase expression by histone-like protein H-NS of Escherichia coli.Semantic proximity Read ↗

Limited functional conservation of a global regulator among related bacterial genera: Lrp in Escherichia, Proteus and Vibrio.Semantic proximity Read ↗

Control of Escherichia coli lysyl-tRNA synthetase expression by anaerobiosis.Semantic proximity Read ↗

Global versus local regulatory roles for Lrp-related proteins: Haemophilus influenzae as a case study.Semantic proximity Read ↗

Transcription of the trp operon in Lactococcus lactis is controlled by antitermination in the leader region.Semantic proximity Read ↗

Leucine-responsive regulatory protein (Lrp) acts as a virulence repressor in Salmonella enterica serovar Typhimurium.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.