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Article

Novel ERBB4 juxtamembrane splice variants are frequently expressed in childhood medulloblastoma

30 May 2001

Abstract excerpt

We recently reported a significant relationship between tumor cell expression of the ERBB4 receptor, the most recently described member of the epidermal growth factor receptor family, and aggressive tumor phenotype in childhood medulloblastoma. Two alternative juxtamembrane (JM) isoforms of the ERBB4 receptor have been described. Termed JMa and JMb, these variants possess different receptor processing and...

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Identifiers

PMID: 11391800
DOI: 10.1002/gcc.1146

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