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Article

Fatal connections: when DNA ends meet on the nuclear matrix.

Journal of cellular biochemistry. Supplement - 1 Jan 2000

Bode J, Benham C, Ernst E, Knopp A, Marschalek R, Strick R, Strissel P

Abstract excerpt

A damaged nucleus has long been regarded simply as a "bag of broken chromosomes," with the DNA free ends moving around and forming connections with randomly encountered partners. Recent evidence shows this picture to be fundamentally wrong. Chromosomes occupy specific nuclear domains within which only limited movement is possible. In a human diploid nucleus, 6.6 x 10(9) base pairs (bp) of DNA are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11389527
DOI: 10.1002/1097-4644(2000)79:35+<3::aid-jcb1121>3.0.co;2-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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