Article
Meiotic Chromosome Contacts as a Plausible Prelude for Robertsonian Translocations.
Genes - 2 Apr 2020
Matveevsky Sergey, Kolomiets Oxana, Bogdanov Aleksey, Alpeeva Elena, Bakloushinskaya Irina
Abstract excerpt
Robertsonian translocations are common chromosomal alterations. Chromosome variability affects human health and natural evolution. Despite the significance of such mutations, no mechanisms explaining the emergence of such translocations have yet been demonstrated. Several models have explored possible changes in interphase nuclei. Evidence for non-homologous chromosomes end joining in meiosis is scarce, and is...
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