Article
Prognostic value of p53 mutations in patients with locally advanced esophageal carcinoma treated with definitive chemoradiotherapy.
Journal of gastroenterology - 1 May 2001
Ito T, Kaneko K, Makino R, Ito H, Konishi K, Kurahashi T, Kitahara T, Mitamura K
Abstract excerpt
PURPOSE: A significant correlation has been found between p53 mutation and response to chemotherapy or radiotherapy. To determine the prognostic value of p53 mutation in patients with locally advanced esophageal carcinoma treated with definitive chemoradiotherapy, p53 mutation was analyzed using the biopsied specimens taken for diagnosis. METHODS: Concurrent chemoradiotherapy was performed for 40 patients with...
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