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Article

Seed and soil revisited: contribution of the organ microenvironment to cancer metastasis.

Surgical oncology clinics of North America - 1 Apr 2001

Fidler I J

Abstract excerpt

The outcome of cancer metastasis depends on multiple interactions (cross-talk) between selected metastatic cells and homeostatic mechanisms unique to some organ microenvironments. The organ microenvironment can influence the biology of cancer growth, angiogenesis, and metastasis in several different ways. Therapy of metastasis, therefore, should be targeted against metastatic tumor cells and the homeostatic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11382586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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