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Article

Human surfactant protein--A gene locus for genetic studies in the Finnish population.

Disease markers - 1 Jan 2000

Rämet M, Haataja R, Marttila R, Hämäläinen A M, Knip M, Hallman M

Abstract excerpt

Lung surfactant lowers the surface tension but surfactant proteins also have other functions. Surfactant protein A (SP-A) has a well-defined role in innate immunity. The gene locus for human SP-A genes is in chromosome 10q21 through q24 and consists of two highly homologous functional SP-A genes (SP-A1 and SP-A2) and a pseudogene. Several alleles that differ by a single amino acid have been identified for both...

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Identifiers

PMID: 11381191
DOI: 10.1155/2000/914814
PMCID: PMC3850821

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