Article
Human SP-A locus: allele frequencies and linkage disequilibrium between the two surfactant protein A genes.
American journal of respiratory cell and molecular biology - 1 Oct 1996
Floros J, DiAngelo S, Koptides M, Karinch A M, Rogan P K, Nielsen H, Spragg R G, Watterberg K, Deiter G
Abstract excerpt
Two surfactant protein A (SP-A) genes and several alleles for each SP-A locus have been previously described. In this report we investigate the potential usefulness of the SP-A loci as markers for genetic studies. We establish conditions that allow the identification of alleles with very similar sequences; We also determine the degree of polymorphism for each SP-A locus: The heterozygosity and polymorphism...
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