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Article

Plasma alpha1-antichymotrypsin in Alzheimer's disease; relationships with APOE genotypes.

Neurobiology of aging - 1 Jan 2000

Scacchi R, Ruggeri M, Gambina G, Martini M C, Ferrari G, Corbo R M

Abstract excerpt

Inflammatory processes are thought to be important contributors to the pathogenesis of Alzheimer's disease (AD). alpha1-antichymotrypsin (ACT) is a proteinase inhibitor characteristic of acute-phase inflammation and has been identified in amyloid plaques. We analyzed the plasma ACT levels in a sample of subjects with late-onset AD and correspondent controls. Plasma ACT was higher in AD patients (62.8 +/- 20.2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11378247
DOI: 10.1016/s0197-4580(00)00246-3

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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