Article
Male reproductive defects caused by puromycin-sensitive aminopeptidase deficiency in mice.
Molecular endocrinology (Baltimore, Md.) - 1 Jun 2001
Osada T, Watanabe G, Kondo S, Toyoda M, Sakaki Y, Takeuchi T
Abstract excerpt
Male reproductive performance is composed of two principal elements, copulation and spermatogenesis. A wealth of literature has described the intricate web of endocrine events underlying these biological processes. In the present study we show that puromycin-sensitive aminopeptidase (Psa)-deficient mice are infertile, lack copulatory behavior, and have impaired spermatogenesis. The reproductive deficits of the...
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