Article
Protein overexport in a Saccharomyces cerevisiae mutant depends on mitochondrial genome integrity and function.
Microbiological research - 1 Jan 2001
Alexandar I, Venkov P, Del Giudice A, Wolf K, Massardo D R, Del Giudice L
Abstract excerpt
The wild-type yeast Saccharomyces cerevisiae (S. cerevisiae) is able to export less than 1 percent of the protein to be secreted. The reasons for retention of most of the secretory proteins on the cell surface of S. cerevisiae are unknown. Recently, temperature-sensitive (ts) mutants of S. cerevisiae showing an oversecretion phenotype were isolated. In order to study the influence of the mitochondrial genome...
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