Article
Aspartame effect in sickle cell anemia.
Clinical pharmacology and therapeutics - 1 May 2001
Manion C V, Howard J, Ogle B, Parkhurst J, Edmundson A
Abstract excerpt
OBJECTIVE: To examine the in vitro and in vivo attributes of aspartame and to determine its efficacy for treating sickle cell anemia. RATIONALE: Aspartame (l-aspartyl-l-phenylalanine methyl ester) binds with 2 human Bence Jones proteins. The proteins (Mcg and Sea) showed phenylalanine penetrating...
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