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Article

Polymorphism of the promoter region of prostacyclin synthase gene is not related to essential hypertension.

American journal of hypertension - 1 May 2001

Nakayama T, Soma M, Takahashi Y, Rehemudula D, Tobe H, Sato M, Uwabo J, Kunimoto M, Izumi Y, Kanmatsuse K

Abstract excerpt

An impaired synthesis of prostacyclin has been implicated in the development of essential hypertension (EH). We therefore investigated whether there is an association between the prostacyclin synthase (PGIS) gene and EH using a variable number of tandem repeats (VNTR) polymorphism in the promoter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11368458
DOI: 10.1016/s0895-7061(00)01256-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11368458-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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