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Article

Cell cycle checkpoint and apoptosis induction in glioblastoma cells and fibroblasts irradiated with carbon beam.

Journal of radiation research - 1 Jul 2007

Tsuboi Koji, Moritake Takashi, Tsuchida Yukihiro, Tokuuye Koichi, Matsumura Akira, Ando Koichi

Abstract excerpt

This study was conducted in order to evaluate the cytotoxicity of high linear-energy-transfer (LET) ionizing radiation (IR) on glioblastoma cells and fibroblasts using different modes of cell inactivation assays. Two human glioblastoma cell lines with or without p53-mutation, and fibroblasts were used as materials. Gamma rays and 290 MeV/u carbon beams with LET values of 20, 40, 80 keV/mum were used. To evaluate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17548940
DOI: 10.1269/jrr.06081

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