Article
Lipid metabolism in zebrafish.
Methods in cell biology - 1 Jan 2004
Ho Shiu-Ying, Thorpe Juanita L, Deng Yun, Santana Evelyn, DeRose Robert A, Farber Steven A
Abstract excerpt
Forward genetics is an unbiased methodology to discover new genes or functions of genes. At the present, the zebrafish is one of the few vertebrate systems where large-scale forward genetic studies are practical. Fluorescent lipid labeling of zebrafish larvae derived from families created from ENU-mutagenized fish enabled us to perform a large scale in vivo screen to identify mutants with perturbed lipid...
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