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Investigating the role of lipid genes in liver disease using fatty liver models of alcohol and high fat in zebrafish ( Danio rerio )

31 Aug 2023

Abstract excerpt

BACKGROUND: Accumulation of lipid in the liver is the first hallmark of both alcohol-related liver disease (ALD) and non-alcohol-related fatty liver disease (NAFLD). Recent studies indicate that specific mutations in lipid genes confer risk and might influence disease progression to irreversible liver cirrhosis. This study aimed to understand the function/s of lipid risk genes driving disease development in...

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PMID: 37650211
DOI: 10.1111/liv.15716

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