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Article

A Novel Role for Bone Morphogenetic Proteins in the Synthesis of Follicle-Stimulating Hormone*

1 Jun 2001

Abstract excerpt

FSH is produced in pituitary gonadotropes as an alpha/beta heterodimer, and synthesis of the beta-subunit is the rate-limiting step in overall FSH production. Synthesis of FSHbeta can be regulated by activin and inhibin, both of which are members of the transforming growth factor-beta superfamily. Bone morphogenetic proteins (BMPs) also belong to the transforming growth factor-beta family and are multifunctional...

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Identifiers

PMID: 11356673
DOI: 10.1210/endo.142.6.8159

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