Article
ACE I/D gene polymorphism predicts renal damage in congenital uropathies.
Pediatric nephrology (Berlin, Germany) - 1 Aug 1999
Hohenfellner K, Hunley T E, Brezinska R, Brodhag P, Shyr Y, Brenner W, Habermehl P, Kon V
Abstract excerpt
We investigated angiotensin converting enzyme gene (ACE I/D) polymorphism as a risk for progressive renal damage in congenital uropathies. The ACE I/D genotype was determined in 196 Caucasian patients with congenital uropathies and 163 individuals with no clinical or sonographic evidence of any urological malformations. The study group included patients with ureteropelvic junction obstruction (n=49), primary...
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