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Article

Analysis of MDM2 and TP53 genes in canine liposarcoma.

Scientific reports - 18 Jun 2024

Muscatello Luisa Vera, de Biase Dario, Maloberti Thais, di Oto Enrico, Tallini Giovanni, Pellegrino Valeria, Bacci Barbara, Roccabianca Paola, Lepri Elvio, Crippa Luca, Avallone Giancarlo

Abstract excerpt

Canine liposarcoma is an uncommon tumor that shares morphological similarities with its human counterpart. In dogs, the genetic features of this tumor are unknown and, based on immunohistochemical studies, amplification of the gene MDM2 and the mutation of TP53 are suspected. In this study 51 cases of primary liposarcomas were immunohistochemically stained for MDM2 and p53 and subjected to fluorescent in situ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38890407
DOI: 10.1038/s41598-024-64963-z
PMCID: PMC11189432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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