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Article

Functional analysis of conserved structural elements in yeast syntaxin Vam3p.

The Journal of biological chemistry - 27 Jul 2001

Wang Y, Dulubova I, Rizo J, Südhof T C

Abstract excerpt

Vam3p, a syntaxin-like SNARE protein involved in yeast vacuole fusion, is composed of a three-helical N-terminal domain, a canonical SNARE motif, and a C-terminal transmembrane region (TMR). Surprisingly, we find that the N-terminal domain of Vam3p is not essential for fusion, although analogous domains in other syntaxins are indispensible for fusion and/or protein-protein interactions. In contrast to the...

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Source

Identifiers

PMID: 11349128
DOI: 10.1074/jbc.M101644200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Functional analysis of conserved structural elements in yeast syntaxin Vam3p.PMID 11349128Read ↗

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