Article
Cutting edge: a NK complex-linked locus governs acute versus latent herpes simplex virus infection of neurons.
Journal of immunology (Baltimore, Md. : 1950) - 15 May 2001
Pereira R A, Scalzo A, Simmons A
Abstract excerpt
Herpes simplex causes latent infections that periodically reactivate. Specific immunization attempts are failing to control herpes, prompting a fresh look at which host responses predominate. We report a NK complex-linked genetic locus, Rhs1, whose alleles influence the magnitude of experimental herpes simplex. Rhs1 provided rapid control of primary infection but caused a reciprocal increase in the number of...
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