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Molecular Mechanisms of Cell Cycle Block by Methionine Restriction in Human Prostate Cancer Cells

1 Sept 2000

Abstract excerpt

Previous studies have shown that dietary or pharmacological methionine restriction inhibits growth of human prostate cancer cells in vitro or as xenografts in mice. We undertook the present studies to clarify the molecular mechanisms by which methionine restriction inhibits prostate cancer cell growth. We found that PC-3 and DU 145 cells stopped proliferating within six days in growth medium containing...

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PMID: 11341037
DOI: 10.1207/s15327914nc381_17

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