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A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension.

Cancer treatment reviews - 1 Oct 2012

Cavuoto Paul, Fenech Michael F

Abstract excerpt

Methionine is an essential amino acid with many key roles in mammalian metabolism such as protein synthesis, methylation of DNA and polyamine synthesis. Restriction of methionine may be an important strategy in cancer growth control particularly in cancers that exhibit dependence on methionine for survival and proliferation. Methionine dependence in cancer may be due to one or a combination of deletions,...

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Identifiers

PMID: 22342103
DOI: 10.1016/j.ctrv.2012.01.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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