Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRCA1/2 testing: complex themes in result interpretation.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 May 2001

Peshkin B N, DeMarco T A, Brogan B M, Lerman C, Isaacs C

Abstract excerpt

Since the cloning of BRCA1 and BRCA2, genetic testing for breast and ovarian cancer susceptibility has become more widespread. However, interpretation of test results is not always straightforward. To illustrate this point, five vignettes adapted from actual cases are presented. As these cases demonstrate, in many high-risk families, a deleterious mutation in BRCA1 or BRCA2 is not identified in an affected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA2 Protein
Share to Breast Neoplasms
Share to Genes, BRCA1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Counseling

Share to Genetic Variation

Share to Neoplasm Proteins

Share to Risk Assessment

Share to Transcription Factors

Source

Identifiers

PMID: 11331335
DOI: 10.1200/JCO.2001.19.9.2555

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRCA1/2 testing: complex themes in result interpretation.PMID 11331335Read ↗

Genetic testing and interpretive complexity: a BRCA1 gene mutation example.Semantic proximity Read ↗

Challenges in managing genetic cancer risk: a long-term qualitative study of unaffected women carrying BRCA1/BRCA2 mutations.Semantic proximity Read ↗

"It wasn't just for me": Motivations and implications of genetic testing for women at a low risk of hereditary breast and ovarian cancer syndrome.Semantic proximity Read ↗

BRCA1 and BRCA2 gene mutations: decision-making dilemmas concerning testing and management.Semantic proximity Read ↗

An update on DNA-based BRCA1/BRCA2 genetic counseling in hereditary breast cancer.Semantic proximity Read ↗

BRCA1 and BRCA2 genetic testing-pitfalls and recommendations for managing variants of uncertain clinical significance.Semantic proximity Read ↗

Professional challenges in cancer genetic testing: who is the patient?Semantic proximity Read ↗

Misinterpreting the Results: Patient Misconceptions about Genetic Cancer Risk after Obstetrical Carrier Screening Shortened Title: Perceptions of Genetic Cancer Risk in Prenatal Carrier ScreeningSemantic proximity Read ↗

Clinical interpretation and recommendations for patients with a variant of uncertain significance in BRCA1 or BRCA2: a survey of genetic counseling practice.Semantic proximity Read ↗

Genetic testing for women previously diagnosed with breast/ovarian cancer: examining the impact of BRCA1 and BRCA2 mutation searching.Semantic proximity Read ↗

Misinterpreting the results: patient misconceptions about genetic cancer risk after obstetrical carrier screening.Semantic proximity Read ↗

Variants of uncertain significance in BRCA testing: evaluation of surgical decisions, risk perception, and cancer distress.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.