Article
Challenges in managing genetic cancer risk: a long-term qualitative study of unaffected women carrying BRCA1/BRCA2 mutations.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Sept 2015
Caiata-Zufferey Maria, Pagani Olivia, Cina Viviane, Membrez Véronique, Taborelli Monica, Unger Sheila, Murphy Anne, Monnerat Christian, Chappuis Pierre O
Abstract excerpt
PURPOSE: Women carrying BRCA1/BRCA2 germ-line mutations have an increased risk of developing breast/ovarian cancer. To minimize this risk, international guidelines recommend lifelong surveillance and preventive measures. This study explores the challenges that unaffected women genetically predisposed to breast/ovarian cancer face in managing their risk over time and the psychosocial processes behind these...
Topics
- Adult
- Attitude of Health Personnel
- BRCA1 Protein
- BRCA2 Protein
- Breast Neoplasms
- Female
- Genes, BRCA1
- Genes, BRCA2
- Genetic Predisposition to Disease
- Genetic Testing
- Germ-Line Mutation
- Guideline Adherence