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Article

Production of Lentiviral Vectors for Transducing Cells from the Central Nervous System

24 May 2012

Abstract excerpt

Efficient gene delivery in the central nervous system (CNS) is important in studying gene functions, modeling neurological diseases and developing therapeutic approaches. Lentiviral vectors are attractive tools in transduction of neurons and other cell types in CNS as they transduce both dividing and non-dividing cells, support sustained expression of transgenes, and have relatively large packaging capacity and...

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PMID: 22664962
DOI: 10.3791/4031

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