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Article

Polymorphism of CD44 influences the efficacy of CD34(+) cells mobilization in patients with hematological malignancies.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Jul 2014

Szmigielska-Kaplon Anna, Szemraj Janusz, Hamara Katarzyna, Robak Marta, Wolska Anna, Pluta Agnieszka, Czemerska Magdalena, Krawczynska Anna, Jamroziak Krzysztof, Szmigielska Katarzyna, Robak Tadeusz, Wierzbowska Agnieszka

Abstract excerpt

In the last decade, peripheral blood was the main source of hematopoietic stem cells (HSC) for autologous and allogeneic transplantation. The exact mechanisms of HSC mobilization are still not clear and the efficacy of the procedure is hardly predictable. Ligand-receptor interactions of adhesion molecules, such as SDF1/CXCR4, VLA4/VCAM-1, or CD44/osteopontin, play an important role in homing of HSC in the...

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Share to Antigens, CD34
Share to Blood Component Removal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematologic Neoplasms

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Source

Identifiers

PMID: 24680978
DOI: 10.1016/j.bbmt.2014.03.019

Genes

CXCR4

Provenance

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Polymorphism of CD44 influences the efficacy of CD34(+) cells mobilization in patients with hematological malignancies.PMID 24680978Read ↗

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