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Article

Associations of the CTLA-4 polymorphisms with type 1 diabetes in a Chilean population: case-parent design.

Diabetes research and clinical practice - 1 Sept 2009

Angel Bárbara, Balic Iván, Santos José Luis, Codner Ethel, Carrasco Elena, Pérez-Bravo Francisco

Abstract excerpt

CTLA-4 plays a key role in T cells regulation. We analysed the CTLA-4 +49A/G and -318C/T polymorphisms in 178 cases of type 1 diabetes and their parents (534 individuals) from Santiago, Chile. A significant overall association with T1D (p=0.028) was observed, possibly due to an overtransmission o...

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Identifiers

PMID: 19592124
DOI: 10.1016/j.diabres.2009.05.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19592124-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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