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Article

Molecular aspects of HLA class II alphabeta heterodimers associated with IDDM susceptibility and protection.

Reviews in immunogenetics - 1 Jan 2000

Ettinger R A, Nepom G T

Abstract excerpt

HLA-DQ alleles are strongly associated with IDDM susceptibility and protection. Studies assessing the molecular properties of HLA-DR, a HLA class II locus in linkage disequilibrium with HLA-DQ, have made substantial contributions toward elucidating the structure and function of HLA class II molecules. Reports on the molecular properties of HLA-DQ are now following and have revealed interesting observations...

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PMID: 11324697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Molecular aspects of HLA class II alphabeta heterodimers associated with IDDM susceptibility and protection.PMID 11324697Read ↗

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Insulin dependent diabetes mellitus susceptibility or protection may be determined by certain HLA-DQ molecules.Semantic proximity Read ↗

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Cross-ethnic group comparisons of HLA class II alleles and insulin dependent diabetes mellitus.Semantic proximity Read ↗

Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus.Semantic proximity Read ↗

Implication of specific DQB1 alleles in genetic susceptibility and resistance by identification of IDDM siblings with novel HLA-DQB1 allele and unusual DR2 and DR1 haplotypes.Semantic proximity Read ↗

The role of DQ alpha-beta heterodimers in genetic susceptibility to insulin-dependent diabetes.Semantic proximity Read ↗

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DRB1*0403 protects against IDDM in Caucasians with the high-risk heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 genotype. Belgian Diabetes Registry.Semantic proximity Read ↗

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