Article
[Poly(AT) polymorphism in DNA repair gene XPC and lung cancer risk].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Nov 2003
Wang Yong-gang, Xing De-yin, Tan Wen, Wang Liang-jun, Tang Ping-zhang, Lin Dong-xin
Abstract excerpt
OBJECTIVE: It has been shown that suboptimal DNA repair capacity is associated with cancer risk and that a poly(AT) polymorphism in XPC gene (XPC PAT) may influence DNA capacity. This study was designed to assess the relationship between XPC PAT polymorphism and susceptibility to lung cancer in the Chinese population. METHODS: XPC genotypes were determined by PCR methods in 509 healthy controls and 597 patients...
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