Article
Y-chromosome transfer induces changes in blood pressure and blood lipids in SHR.
Hypertension (Dallas, Tex. : 1979) - 1 Apr 2001
Kren V, Qi N, Krenova D, Zidek V, Sladká M, Jáchymová M, Míková B, Horky K, Bonne A, Van Lith H A, Van Zutphen B F, Lau Y F, Pravenec M, St Lezin E
Abstract excerpt
Previous studies with chromosome-Y consomic strains of spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats suggest that a quantitative trait locus for blood pressure regulation exists on chromosome Y. To test this hypothesis in the SHR-Brown Norway (BN) model and to study the effects of c...
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