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Article

Rat thymic epithelial cells in culture constitutively secrete IL-1 and IL-6.

International immunology - 1 Nov 1991

Colić M, Pejnović N, Kataranovski M, Stojanović N, Terzić T, Dujić A

Abstract excerpt

To study the in vitro interactions between rat thymic non-lymphoid cells and thymocytes, we established a system for long-term cultivation of thymic epithelial cells (TEC). TEC were cultivated and successfully propagated for over 8 months in RPMI 1640 medium containing 15% FCS, dexamethasone, insulin, epidermal growth factor, and poly-L-lysin as an adhesive matrix. Their epithelial nature has been confirmed using...

Topics

Animals
Cells, Cultured
Epithelial Cells
Epithelium
Fluorescent Antibody Technique
Interleukin-1
Interleukin-6
Phenotype
Rats
T-Lymphocytes
Thymus Gland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1760411
DOI: 10.1093/intimm/3.11.1165

Genes

TEC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1760411-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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