Article
Multiple cellular phenotypes in an insertional mutation in mouse affecting bone development.
Calcified tissue international - 1 Dec 2000
Nadon N L, Doersen C J, Lade D A, Medina K, Thompson L, Rohrer M, Gimble J M
Abstract excerpt
The 6093 line of transgenic mice exhibits altered bone development as a result of an insertional mutation by the transgene. Female transgenic mice show a marked kyphosis as early as 2 weeks of age. Vertebrae from female mice have lower total bone area and mineral content than age-matched, gender-...
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