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Article

Single nucleotide instability without microsatellite instability in rat mammary carcinomas.

Cancer research - 15 Mar 2001

Watanabe N, Okochi E, Hirayama Y, Shimada Y, Yanagihara K, Yoshida M C, Takahashi S, Mochizuki M, Sugimura T, Nagao M, Ushijima T

Abstract excerpt

Mutation frequencies (MnFs) of the lacI transgene and mutation rates (MRs) of the endogenous hprt gene were analyzed in two mammary carcinoma cell lines that we established from mammary carcinomas that had been induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in female lacI-transgenic rats. Using the lacI transgene, corrected MnF, which is the number of independent lacI mutations that occurred...

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PMID: 11289141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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