Article
Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential.
Cancer research - 1 Mar 2001
Bellone G, Carbone A, Sibona N, Bosco O, Tibaudi D, Smirne C, Martone T, Gramigni C, Camandona M, Emanuelli G, Rodeck U
Abstract excerpt
Multiple genetic aberrations contribute to the development of biologically aggressive, clinically malignant colorectal carcinomas (CRCs). Some of these have been linked to inappropriate signaling through the tyrosine kinase moieties of growth factor receptors. We have described previously (G. Bel...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
