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Article

Differential involvement of destrin and cofilin‐1 in the control of invasive properties of Isreco1 human colon cancer cells

21 Jun 2007

Abstract excerpt

Actin depolymerizing factor (ADF)/cofilin family proteins are key regulators of actin filament turnover and cytoskeleton reorganization. The role of cofilin-1 in cell motility has been demonstrated in several cell types but remained poorly documented in the case of colon cancer. In addition, the putative function of destrin (also known as ADF) had not been explored in this context despite the fact that it is...

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PMID: 17583572
DOI: 10.1002/ijc.22911

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