Article
Absence of sodium/iodide symporter gene mutations in differentiated human thyroid carcinomas.
Thyroid : official journal of the American Thyroid Association - 1 Jan 2001
Russo D, Manole D, Arturi F, Suarez H G, Schlumberger M, Filetti S, Derwahl M
Abstract excerpt
Decrease or loss of the sodium iodide (Na+/I-) symporter (NIS) activity influences the suitability of using radioiodine to detect and treat metastatic thyroid tissues. In previous studies, the presence of the NIS transcript, albeit at lower expression levels, has been shown in most thyroid differ...
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