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Article

Sequence requirements for interaction of human herpesvirus 7 origin binding protein with the origin of lytic replication.

Journal of virology - 1 Apr 2001

Krug L T, Inoue N, Pellett P E

Abstract excerpt

As do human herpesvirus 6 variants A and B (HHV-6A and -6B), HHV-7 encodes a homolog of the alphaherpesvirus origin binding protein (OBP), which binds at sites in the origin of lytic replication (oriLyt) to initiate DNA replication. In this study, we sought to characterize the interaction of the HHV-7 OBP (OBP(H7)) with its cognate sites in the 600-bp HHV-7 oriLyt. We expressed the carboxyl-terminal domain of...

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Identifiers

PMID: 11264381
DOI: 10.1128/JVI.75.8.3925-3936.2001
PMCID: PMC114883

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Source receipt: pubmed, retrieved 7 Sept 2026.

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