Article
Type I protein kinase a is localized to interphase microtubules and strongly associated with the mitotic spindle.
Experimental cell research - 1 Apr 2001
Imaizumi-Scherrer T, Faust D M, Barradeau S, Hellio R, Weiss M C
Abstract excerpt
We show here that type I protein kinase A is localized to microtubules during the entire cell cycle in epithelial (hepatoma, cervical carcinoma) and nonepithelial (myoblast) cell lines. The association of the type Ialpha regulatory subunit is very strong in all phases of mitosis, from prophase to cytokinesis. In interphase, the association appears weaker, reflecting perhaps a more dynamic molecular interaction....
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