Article
The autolysin Ami contributes to the adhesion of Listeria monocytogenes to eukaryotic cells via its cell wall anchor.
Molecular microbiology - 1 Mar 2001
Milohanic E, Jonquières R, Cossart P, Berche P, Gaillard J L
Abstract excerpt
Adherence of pathogenic microorganisms to the cell surface is a key event during infection. We have previously reported the characterization of Listeria monocytogenes transposon mutants defective in adhesion to eukaryotic cells. One of these mutants had lost the ability to produce Ami, a 102 kDa autolytic amidase with an N-terminal catalytic domain and a C-terminal cell wall-anchoring domain made up of repeated...
Topics
- Amino Acid Sequence
- Animals
- Bacterial Adhesion
- Cell Wall
- Eukaryotic Cells
- Female
- Humans
- Listeria monocytogenes
- Listeriosis
- Mice
- Molecular Sequence Data
- Mutation
- N-Acetylmuramoyl-L-alanine Amidase
- Sequence Alignment
- Tumor Cells, Cultured
- Virulence