Article
Screening Leishmania donovani-specific genes required for visceral infection.
Molecular microbiology - 1 Jul 2010
Zhang Wen-Wei, Matlashewski Greg
Abstract excerpt
Comparison of the Leishmania infantum genome with Leishmania braziliensis and Leishmania major genomes has identified 25 L. infantum species-specific genes that are absent or pseudogenes in L. major and L. braziliensis. To determine whether these L. infantum species-specific genes are involved in visceral Leishmania infection, we cloned the orthologues of 14 L. infantum species-specific genes from the genetically...
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