Article
Association of the insulin-like growth factor1 gene with myocardial infarction in Japanese subjects.
Hereditas - 1 Oct 2010
Aoi Noriko, Nakayama Tomohiro, Soma Masayoshi, Kosuge Kotoko, Haketa Akira, Sato Mikano, Sato Naoyuki, Asai Satoshi, Matsumoto Koichi
Abstract excerpt
During adult life, the insulin/insulin-like growth factor1 (IGF1) signaling pathway plays an important role in cardiovascular function. Several reports have suggested that low baseline levels of IGF1 increase the risk of fatal ischemic heart disease. Thus, IGF1 may be involved in cardiovascular disease. The aim of the present study was to investigate the relationship between the human IGF1 gene and myocardial...
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