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Article

Fine scale association mapping of disease loci using simplex families.

Annals of human genetics - 1 May 2000

Morris A P, Whittaker J C

Abstract excerpt

We present a new method for the fine scale mapping of disease loci based on samples of simplex families, each containing an affected child. The method is based on a generalisation of a single locus allele transmission model to multiple marker loci. The model is developed under the assumption of a...

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PMID: 11246474
DOI: 10.1017/S0003480000008058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11246474-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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