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Article

Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach.

Molecular psychiatry - 1 Jan 2001

Wang T, Franke P, Neidt H, Cichon S, Knapp M, Lichtermann D, Maier W, Propping P, Nöthen M M

Abstract excerpt

Catechol-O-methyltransferase (COMT) is a major component of the metabolic pathways of neurotransmitters such as dopamine, adrenaline, and noradrenaline. The activity of COMT is known to vary within the population; it exists in common high- and low-activity forms that are determined by a Val --> M...

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Source

Identifiers

PMID: 11244495
DOI: 10.1038/sj.mp.4000803

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-11244495-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Association study of the low-activity allele of catechol-O-methyltransferase and alcoholism using a family-based approach.PMID 11244495Read ↗

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