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Article

Phenotypic characterization of three phylogenetically conserved stem-loop motifs in the mengovirus 3' untranslated region.

Journal of virology - 1 Apr 2001

Duque H, Palmenberg A C

Abstract excerpt

An alignment of cardiovirus sequences led to the prediction of three conserved stem-loops in the 3' untranslated region (UTR) of mengovirus. Deletions of each stem were engineered in mengovirus cDNAs and also in mengovirus replicons, in which part of the viral capsid sequences were replaced with the firefly luciferase gene. The effect of deletion on RNA infectivity and plaque phenotype was evaluated after...

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Identifiers

PMID: 11238838
DOI: 10.1128/JVI.75.7.3111-3120.2001
PMCID: PMC114105

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