Article
The BB-paraoxonase genotype is associated with impaired brachial reactivity after acute hypertriglyceridemia in healthy subjects.
The Journal of clinical endocrinology and metabolism - 1 Mar 2001
Paolisso G, Manzella D, Tagliamonte M R, Barbieri M, Marfella R, Zito G, Bonafè M, Giugliano D, Franceschi C, Varricchio M
Abstract excerpt
The possible relationship between paraoxonase (PON) gene polymorphism and brachial reactivity in healthy adult subjects in the presence of acute hypertriglyceridemia (HT), as a prooxidant factor, was investigated. In 101 healthy subjects the response to flow- induced vasodilatation was measured before and after Intralipid infusion. In the same subjects the A/B PON polymorphism was detected. The frequency was...
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