Article
Human sensitivity to 1,3-butadiene: role of microsomal epoxide hydrolase polymorphisms.
Carcinogenesis - 1 Mar 2001
Abdel-Rahman S Z, Ammenheuser M M, Ward J B
Abstract excerpt
1,3-Butadiene (BD) is a major commodity chemical used in the manufacture of synthetic rubber and various plastics and has been shown to be a potent animal carcinogen and a probable human carcinogen. The bioactivation of BD to reactive epoxides, and the balance between activation and detoxication...
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