Article
Frequent beta-catenin mutations in juvenile nasopharyngeal angiofibromas.
The American journal of pathology - 1 Mar 2001
Abraham S C, Montgomery E A, Giardiello F M, Wu T T
Abstract excerpt
Juvenile nasopharyngeal angiofibromas (JNAs) are locally aggressive vascular tumors occurring predominantly in adolescent males. The pathogenesis of JNAs is unknown. Recently, JNAs have been reported to occur at increased frequency among patients with familial adenomatous polyposis, suggesting that alterations of the adenomatous polyposis coli (APC)/beta-catenin pathway might also be involved in the pathogenesis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.