Juvenile nasopharyngeal angiofibroma: an immunohistochemical characterisation of the stromal cell.

doi:10.1080/00313020802035857

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Article

Juvenile nasopharyngeal angiofibroma: an immunohistochemical characterisation of the stromal cell.

Pathology - 1 Jun 2008

Pauli John, Gundelach Raefe, Vanelli-Rees Alba, Rees Glynn, Campbell Catherine, Dubey Siba, Perry Chris

Abstract excerpt

AIMS: Juvenile nasopharyngeal angiofibroma (JNA) is a rare tumour occurring almost exclusively in young adult males. Although histologically benign, it can be locally aggressive with a significant recurrence rate. The finding of activating beta-catenin gene mutations in the stromal cells indicates these are the neoplastic cells and supports the association of JNA and familial adenomatous polyposis (FAP). Previous...

Topics

Angiofibroma
Biomarkers, Tumor
Humans
Immunoenzyme Techniques
Nasopharyngeal Neoplasms
Neoplasm Proteins
Phenotype
Stromal Cells
Vimentin

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Open in PubMed

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PMID: 18446631
DOI: 10.1080/00313020802035857

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