Article
The bone marrow stromal microenvironment influences myeloma therapeutic response in vitro.
Leukemia - 1 Feb 2001
Cheung W C, Van Ness B
Abstract excerpt
The bone marrow microenvironment supports growth and differentiation of normal hematopoietic cells and can contribute to malignant growth. Since myeloma cells localize and accumulate in bone marrow, it is important to understand the influence of the bone marrow microenvironment not only on the growth of the malignant cells, but also on the therapeutic response of myeloma cells. Growth factors such as...
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